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disease[disease 词源字典]

disease: [14] Disease and malaise are parallel formations: both denote etymologically an ‘impairment of ease or comfort’. Disease comes from Old French desaise, a compound formed from the prefix dis- ‘not, lacking’ and aise ‘ease’, and in fact at first meant literally ‘discomfort’ or ‘uneasiness’. It was only towards the end of the 14th century that this sense began to narrow down in English to ‘sickness’. (Malaise was borrowed from French malaise, an Old French formation from mal ‘bad’ and aise.)
=> ease, malaise[disease etymology, disease origin, 英语词源]