12. Lysine acetylation is a reversible posttranslational modification of proteins and plays a key role in regulating gene expression.
赖氨酸乙酰化是一种蛋白质可逆的翻译后修饰作用,在基因表达调控中起重要作用。
来自互联网
13. Histone acetylation and deacetylation can regulate many chromosome functions, such as gene expression and chromosome segregation.
组蛋白乙酰化和去乙酰化可调节染色体的多种功能,例如基因表达和染色体分离等。
来自互联网
14. It has been known for some time that the acetylation of N-termini of core histones in nucleosome is associated with gene activation.
人们很早就注意到,真核细胞中核小体核心组蛋白N-端尾部的乙酰化水平与基因活化密切相关。
来自互联网
15. With in-depth study, we found that protein acetylation have great influence in the secretion of cytokines, generation of NO and so on.
随着研究的深入,发现蛋白质乙酰化状态对细胞因子的分泌、NO的产生等方面均有较大的影响。
来自互联网
16. As in the Alzheimer's mice, drugs that boosted histone acetylation improved the older mice's performance on tests of rodent cognition.
如同阿尔茨海默病鼠,增强组蛋白乙酰化的药物改善了年老小鼠在认知测试中的表现。
来自互联网
17. The copolymer after acetylation and phosphonylation can react with dibutyl amine to yield the corresponding dibutylamidophosphate resin.
经乙酰化,膦化反应后的共聚体可以与二正丁胺作用制得膦酰胺树脂。
来自互联网
18. The methods of the modification of phospholipids were summarized, such as hydroxylation, hydrogenation, hydrolyzation, acetylation, and so on.
本文主要介绍了磷脂的化学改性方法,例如:羟基化、氢化、酶水解、酰化等。
来自互联网
19. There are some other ways to analyzed the contents of menthol and menthone, such as polarimetry, refraction index method and acetylation method.
薄荷醇和薄荷酮含量的测定方法有旋光测定法、折光指数法及乙酰化法。
来自互联网
20. Histone acetylation and de-acetylation can change the structure of chromatin, involving in gene expression regulation and nuclear reprogramming.
组蛋白乙酰化和去乙酰化可以改变染色质的结构,参与基因的表达调控和重编程。
来自互联网
21. Histone acetylation has a close relation with some biological effects such as gene transcription, and is catalyzed by histone acetyltransferases.
组蛋白乙酰化与基因转录等生物效应有密切的关系,组蛋白乙酰化主要是由组蛋白乙酸转移酶催化的。
来自互联网
22. In additional experiments, the researchers injected a drug into the brains of older mice to counter the drop in acetyl tag attachment, or acetylation.
23. The acetylation of histone is related to gene expression and regulation, which takes part in the pathological courses of all kinds of lung diseases.
组蛋白乙酰化修饰与基因的表达调控相关,参与了各种肺部疾病的病变过程。
来自互联网
24. Gene expression is often closely related to the different chemical modification ends of protein, acetylation is a kind of common form of modification.
组蛋白尾端不同的化学修饰往往和基因的表达调控有着密切的关系,乙酰化就是常见的一种修饰形式。
来自互联网
25. Acetylation causes histones to unspool their DNA, thereby allowing gene expression to proceed—so decreased acetylation generally reduces gene expression.
26. Other work has focused on histone acetylation, a chemical modification that unwinds DNA from protein spools called histones, thereby enabling gene activity.
其他的工作集中在组蛋白乙酰化,这种化学修饰可以使DNA从组蛋白缠绕中解离出来,产生基因活性。
来自互联网
27. The genetic switch involves acetylation, the introduction of an acetyl group into a molecule at the DNA level of chromatin resulting in genetic transcription.
基因“开关”涉及乙酰化作用,也就是将乙酰基群在染色质的DNA水平上引入到分子中,由此完成基因转录。
来自互联网
28. Histone deacetylase inhibitors increase the acetylation level of histone as well as some non-histone proteins, and specifically modulate some gene expression.
29. Combined with the results of histone deactylase inhibitor, it is suggested that histone acetylation plays an important role in hsp gene transcription regulation.
结合以上去乙酞化酶抑制剂的实验结果,我们认为组蛋白乙酞化修饰参与了热休克基因的表达调控。
来自互联网
30. Combined with the results of histone deactylase inhibitor, it is suggested that histone acetylation plays an important role in hsp gene transcription regulation.