1. But yohimbine could not antagonize the central hypotensive action of GABA, while picrotoxin could entirely block it.
但是育亨宾不能阻断侧脑室注射GABA的中枢降压作用,而苦味毒则能完全阻断其降压效应。
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2. Pretreatment of either isoniazid, an aminoacid decarboxylase inhibitor, or GABA receptor antagonist picrotoxin prevented thedepressant effect of diazepam on the amplitude of phrenic discharge.
3. It was found that the antagonist picrotoxin was unable to block the liver fluke to the excitatory effect of GABA, while it could partially block the roundworm to the inhibitory effect of GABA.
颉颃药印防己毒不能阻断GABA对肝片形吸虫的兴奋效应,但能部分阻断对鸡蛔虫的抑制效应。
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4. Conclusion: Melatonin does not exhibit its potentiation sleeping time in mice through melatonin 3 receptor. Hypnotic activity of melatonin may be mediated through picrotoxin site on GABAA receptor.
5. Objective to observe the kindling model of Sprague Dawley (SD) rats induced by injection of different doses of picrotoxin (PTX) intraperitoneally, and to evaluate the effect of the drug on the model.
目的:观察不同剂量印防已毒(PTX)致SD鼠慢性点燃癫痫模型及药物对该模型的影响。
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6. In midbrain slices from rats treated with saline or a single dose of cocaine, LTP could not be induced in VTA dopamine neurons unless GABA-mediated inhibition was reduced by bicuculline or picrotoxin.
7. In midbrain slices from rats treated with saline or a single dose of cocaine, LTP could not be induced in VTA dopamine neurons unless GABA-mediated inhibition was reduced by bicuculline or picrotoxin.