"Stimulating the secretion of bile by the liver; designating this action or effect", 1920s; earliest use found in Journal of Pharmacological and Experimental Therapeutics. From chole- + -retic, after German choleretisch and Cholereticum respectively, both ultimately after Cholerese amount of bile secreted by the liver in a specific time.[choleretic etymology, choleretic origin, 英语词源]